Fatty Liver Disease - what you need to know

Fatty Liver disease is something my daughter was diagnosed with at the age of 11. In the 2 years since she has had the disease I have learned a lot. Unfortunately I have learned NOTHING from doctors. They do not understand this disease and they basically pat the patient on the head and tell them to lose weight and exercise and everything will? be ok. My daughter has tried and has not been successful and I now know that is because when your liver is not functioning correctly nothing internally is functioning right.

I am now driven to start a movement regarding this disease. Education of the general population is key. We think of sick livers being caused by alcohol or sharing dirty needles, we do not think of it associated to the ice cream cone we enjoyed at baskin robbins!

This disease has been diagnosed in children as young as 4, that is very scary, my 13 year old has a chronic illness and that is scary! These are CHILDREN, chronic illness is for the middle aged folks, the elderly even!! If its showing up in our kids our world is in serious trouble and we need to change things NOW!!

Feed your children organic foods, fresh fruits , fresh veggies, get your meat from a butcher , go back to basics please! No more convenience foods filled with chemicals…if you don’t understand what is on the side of the label why are you eating it!

I have approached the Canadian Liver Foundation about starting a sister foundation dedicated to Fatty Liver disease. I truly believe this will be as big as diabetes in the next 20 years and that a lot of us have it already without major symptoms. Once the major symptoms are showing up , you have damaged your liver and your goal is to prevent further deterioration! The next time you have a blood test ask to have your AST and ALT? levels checked, even if you are skinny on the outside you may be fat on the inside, so do not take it for granted that this is only a disease of the obese!

The sooner you find out about the condition of the liver , the easier it is to resolve with diet and exercise.

Hugs….and nope did not get that job from last week …but may have found my calling instead!

See my support group in facebook to understand this even further!

http://www.facebook.com/group.php?gid=40124237301

Michelle

Posted in Megan's Health Battle, fatty liver, gethealthywithmichelle, weight loss | Tagged toxins, nutrition, lifestyle, nafld, fatty liver, nash | Leave a Comment

View the original article here

Fatty Liver Matters

Please tell me you already knew this.

People with non-alcoholic fatty liver disease (NAFLD), a condition that often accompanies obesity and type 2 diabetes, have higher mortality rates than the general population, a new Swedish study found.

Patients with NAFLD were 69% percent more likely to die than the general Swedish population (standardized mortality ratio 1.69, 95% CI 1.24 to 2.25), according to a report in the February issue of Hepatology.

Patients with non-alcoholic steatohepatitis (NASH), a condition where fat buildup causes liver inflammation, were at 86% higher risk (95% CI 1.19 to 2.76; P=0.007).

View the original article here

Vitamin E Beneficial to patients with Nonalcoholic Fatty Liver

A new study (PIVENS?trial) indicated that patients with nonalcoholic fatty liver might benefits?from natural form of vitamin E (800 IU/day), but not from pioglitazone?(Actos).??

Nonalcoholic fatty liver or Nonalcoholic Steatohepatitis (NASH) currently affects about 4% of the American population and there is no approved therapy.? About 15% of patients with NASH progress to cirrhosis and patients with NASH experience fatty liver disease, insulin resistance, and obesity.

The new study is a multicenter?trial involving 247 nondiabetic adults with biopsy-proven NASH. Patients were allocated to the following 3 arms:?

80 patients to the insulin-sensitizer?pioglitazone?(Actos) (30 mg once daily)84 patients to vitamin E (800 IU/day)83 patients to placebo?

After 96 weeks, patients in the vitamin E therapy arm was associated with a significantly higher rate of improvement in NASH when compared with placebo (43% vs 19%; P = .001; number needed to treat, 4.2).

However, the difference in the rate of NASH improvement with pioglitazone?compared with placebo did not reach the prespecified 0.025 level of significance (34% vs. 19%; P?= .04; number needed to treat, 6.9).? Even though the pioglitazone?arm did not reach the statistical endpoint, pioglitazone still improve the histology in half of the NASH patients.?

Despite the positive results, the investigator, Dr. Harrison, still emphasized the importance of treating the causes (obesity, prediabetes and frank diabetes).?

In addition to prescribing vitamin E 800 IU/day, Dr. Harrison still aims to reduce patient’s weight (ideally 10% reduction) with diet and exercise up front.? Only in patients who are not able to lose the weight and with advanced disease will he then consider prescribing pioglitazone.

Published online in the April 28, 2010 issue of ?N Engl J Med.

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Filed under: Fatty Liver | Tagged: vitamin E, Fatty Liver, pioglitazone, Actos, NASH

View the original article here

Vitamin E and Fatty Liver

Treating Nonalcoholic Fatty Liver: Pioglitazone or Vitamin E?

Vitamin E is superior to placebo in treating nonalcoholic steatohepatitis, according to a New England Journal of Medicine study. Pioglitazone, although showing some efficacy, did not achieve statistically significant results.

Researchers, pursuing earlier findings that thiazolidinediones and antioxidants can lead to improvements in fatty liver, randomized some 250 nondiabetic patients with nonalcoholic steatohepatitis to 2 years’ treatment with either pioglitazone, vitamin E, or placebo. Improved histologic findings were the study’s primary outcome.

Liver biopsies showed that vitamin E recipients had a higher rate of improvement than those on placebo (43% vs. 19%). The improvement among pioglitazone recipients versus placebo did not reach statistical significance (34% vs. 19%). Both treatments reduced alanine and aspartate aminotransferase levels significantly from baseline values.

To view article, click? HERE

View the original article here

Fatty Liver Disease - what you need to know

April 21, 2010 by gethealthywithme

Fatty Liver disease is something my daughter was diagnosed with at the age of 11. In the 2 years since she has had the disease I have learned a lot. Unfortunately I have learned NOTHING from doctors. They do not understand this disease and they basically pat the patient on the head and tell them to lose weight and exercise and everything will? be ok. My daughter has tried and has not been successful and I now know that is because when your liver is not functioning correctly nothing internally is functioning right.

I am now driven to start a movement regarding this disease. Education of the general population is key. We think of sick livers being caused by alcohol or sharing dirty needles, we do not think of it associated to the ice cream cone we enjoyed at baskin robbins!

This disease has been diagnosed in children as young as 4, that is very scary, my 13 year old has a chronic illness and that is scary! These are CHILDREN, chronic illness is for the middle aged folks, the elderly even!! If its showing up in our kids our world is in serious trouble and we need to change things NOW!!

Feed your children organic foods, fresh fruits , fresh veggies, get your meat from a butcher , go back to basics please! No more convenience foods filled with chemicals…if you don’t understand what is on the side of the label why are you eating it!

I have approached the Canadian Liver Foundation about starting a sister foundation dedicated to Fatty Liver disease. I truly believe this will be as big as diabetes in the next 20 years and that a lot of us have it already without major symptoms. Once the major symptoms are showing up , you have damaged your liver and your goal is to prevent further deterioration! The next time you have a blood test ask to have your AST and ALT? levels checked, even if you are skinny on the outside you may be fat on the inside, so do not take it for granted that this is only a disease of the obese!

The sooner you find out about the condition of the liver , the easier it is to resolve with diet and exercise.

Hugs….and nope did not get that job from last week …but may have found my calling instead!

See my support group in facebook to understand this even further!

http://www.facebook.com/group.php?gid=40124237301

Michelle

Posted in Megan's Health Battle, fatty liver, gethealthywithmichelle, weight loss | Tagged toxins, nutrition, lifestyle, nafld, fatty liver, nash | Leave a Comment

View the original article here

Fatty Liver Matters

Please tell me you already knew this.

People with non-alcoholic fatty liver disease (NAFLD), a condition that often accompanies obesity and type 2 diabetes, have higher mortality rates than the general population, a new Swedish study found.

Patients with NAFLD were 69% percent more likely to die than the general Swedish population (standardized mortality ratio 1.69, 95% CI 1.24 to 2.25), according to a report in the February issue of Hepatology.

Patients with non-alcoholic steatohepatitis (NASH), a condition where fat buildup causes liver inflammation, were at 86% higher risk (95% CI 1.19 to 2.76; P=0.007).

View the original article here

Vitamin E and Fatty Liver

Treating Nonalcoholic Fatty Liver: Pioglitazone or Vitamin E?

Vitamin E is superior to placebo in treating nonalcoholic steatohepatitis, according to a New England Journal of Medicine study. Pioglitazone, although showing some efficacy, did not achieve statistically significant results.

Researchers, pursuing earlier findings that thiazolidinediones and antioxidants can lead to improvements in fatty liver, randomized some 250 nondiabetic patients with nonalcoholic steatohepatitis to 2 years’ treatment with either pioglitazone, vitamin E, or placebo. Improved histologic findings were the study’s primary outcome.

Liver biopsies showed that vitamin E recipients had a higher rate of improvement than those on placebo (43% vs. 19%). The improvement among pioglitazone recipients versus placebo did not reach statistical significance (34% vs. 19%). Both treatments reduced alanine and aspartate aminotransferase levels significantly from baseline values.

To view article, click? HERE

View the original article here